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| Bénédicte Fontaine-Bisson, PhD |
Titre: Personalized Food Products: How Can Nutritional Genomics Help?
Date: 11 novembre 2014
Lieu: Kitakyushu, Japon
Chercheur : Bénédicte Fontaine-Bisson
Abstract
Nutritional genomics is a leading-edge area of research in nutrition which studies interactions between the diet and genome. This includes how dietary patterns or compounds affect gene expression (nutrigenomics) and how genetic differences modify the response to these dietary components (nutrigenetics). Advanced technologies used in nutritional genomics (e.g. genomics / epigenetics, transcriptomics, proteomics and metabolomics) hold tremendous potential to develop health-promoting products and food-derived therapeutics such as functional foods and nutraceuticals. Understanding the unique molecular signature of these diet-derived compounds from gene expression to protein and metabolite interactions should help to improve their efficacy while reducing the risk of side effects. The variability in response to functional foods and nutraceuticals due to differences in genetic backgrounds within and between animal species and human populations also need to be taken into account. Novel foods or supplements being subsequently marketed may in fact be beneficial for some, while ineffective or even detrimental for others. Additional considerations regarding safety, appropriate dosage, purification and contamination need to be addressed before commercialization. Integrating nutritional genomics and system biology approaches in the development of functional foods and nutraceuticals should help to target the right food to the right people and in the right amount for optimal health and disease prevention.
